9 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... tests, Low Platelets ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... tests, Low Platelets ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... polyhydramnios, fetal ... purpura (TTP) • HELLP ... #Obstetrics #OBGyn
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... - History of bleeding ... : INR/PT, aPTT(liver ... K), H. pylori test
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
: • Defect in fetal ... = nonspecific (nausea ... Preeclampsia, HELLP ... Pregnancy #hepatology #obstetrics ... #obgyn #diagnosis
ED Treatment of 
Abnormal Uterine Bleeding 

Hemodynamically unstable 
Resuscitation 
 • ABCs! 
 • Fluids +
coagulopathy Pregnancy test ... pregnancy related cause ... breast cancer, liver ... PO Outpatient OBGYN ... #Management #Obstetrics
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... • Pregnancy: HELLP ... extrahepatic source - Tests ... RBC (hemolysis, bleeding
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
indirect Coombs test ... severe thrombocytopenia ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis
CASTLEMAN DISEASE
Disorder of the immune system with excessive production of IL-6

Castleman’s disease is a rare, heterogeneous
loss, Enlarged liver ... Lab Tests: 1. ... CBC: Anemia and thrombocytopenia ... in MCD and may help ... in diagnosis 9