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Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
• Subcutaneous Nodules ... (Osler's Nodes) ... pathophysiology #diagnosis #signs ... #symptoms #complications
Common organ involvements and symptoms in Sarcoidosis Lung 89-99% - Cough, dyspnoea, wheezing and stridor Skin 16-32% -
involvements and symptoms ... pernio, papules, nodules ... functions Lymph nodes ... #diagnosis #signs ... #symptoms
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Vasculitis, Rheumatoid Nodules ... #rheumatology #signs ... #symptoms
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs ... /Symptoms: - ... artery tender, nodular ... Complications #Signs ... #Symptoms #diagnosis
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
BB-sized, hard nodules ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
: Subcutaneous nodules ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Clinical Features of Infective Endocarditis General - Malaise - Clubbing Cardiac - Murmurs
lesions - Osler's nodes ... #Endocarditis #Symptoms ... #Signs #Features
Stages of Syphilis Early Primary: • Painless chancre • Regional lymphadenopathy Early Secondary: • Fever, malaise • Rash
testing • No symptoms ... • Gummatous • Nodular ... Syphilis #Stages #symptoms ... #signs #diagnosis
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... resistance • Adrenal: Nodular ... Hydroxylase #Deficiency #Signs ... #Symptoms #diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Skin: Rheumatoid nodules ... Arthritis #RA #Signs ... #Symptoms #diagnosis
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