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diagnosis management differential clinical algorithm causes peds pediatrics pathophysiology cardiology treatment hematology radiology signs comparison symptoms neurology pulmonary rheumatology syndrome
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Immunoglobulin E (IgE ... infections Non-IgE ... Differential #Urticaria #IgE ... #Mediated #NonIgE
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 Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Mechanisms Type I - lgE ... Allergen-specific lgE ... cross-linking of lgE ... antigen - IgG ... or IgM antibody
IgM and Non-IgM - Risk and Type of Progression #EBM #Honc #MGUS #Progression #IgM #NonIgM #MultipleMyeloma
IgM and Non-IgM ... #Progression #IgM ... #NonIgM #MultipleMyeloma
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Mediator: lgE ... Immunological Mediator: IgM ... + IgG • Immunological ... Immunological Mediator: IgG ... Contact Dermatitis (ie
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type I - lgE-Mediated ... Anaphylaxis) Type II - IgG ... or IgM Cytotoxic
Causes of Nausea and Vomiting - Differential Algorithm #Diagnosis #EM #IM #Causes #Nausea #Vomiting #Differential #NonGI
#Differential #NonGI
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF,
You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
notice there is an IgM ... and an IgG core ... The presence of IgM ... IgM anti-HBc is ... The presence of IgG
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
1: Monoclonal IgM ... (rarely IgG/lgA ... 2: Monoclonal IgM ... and polyclonal IgG ... and polyclonal IgG
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
AIHA: - 70%; IgG ... mediated - DAT: IgG ... AIHA: - 20%; IgM ... mediated - DAT: IgG
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