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diagnosis im management differential em algorithm clinical ddxof treatment cardiology causes nejm table hematology rheumatology pathophysiology pulmonary workup comparison nephrology
IgM and Non-IgM - Risk and Type of Progression #EBM #Honc #MGUS #Progression #IgM #NonIgM #MultipleMyeloma
IgM and Non-IgM ... #Progression #IgM ... #NonIgM #MultipleMyeloma
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
1: Monoclonal IgM ... may be seen when IgM ... 2: Monoclonal IgM ... 25%): Polyclonal IgM ... 3: Oligoclonal IgM
Causes of Nausea and Vomiting - Differential Algorithm #Diagnosis #EM #IM #Causes #Nausea #Vomiting #Differential #NonGI
Diagnosis #EM #IM ... #Differential #NonGI
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Immunoglobulin E (IgE ... infections Non-IgE ... Differential #Urticaria #IgE ... #Mediated #NonIgE
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 You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
notice there is an IgM ... The presence of IgM ... IgM anti-HBc is ... core antibody and IgM ... ) simply means IgM
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF,
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
AIHA: - 70%; IgG ... mediated - DAT: IgG ... AIHA: - 20%; IgM ... mediated - DAT: IgG
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
IgM MGUS: • Serum ... IgM monoclonal ... can progress to IgM ... myeloma Non-IgM ... protein level (non-IgM
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
or IgM - Cell-bound ... antigen - IgG ... or IgM antibody ... Type Ill - IgG and ... IgM - Soluble antigen
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
with small (<1.5 gm ... /dL) IgM MGUS, low-risk ... MGUS (IgG type, ... - protein <1.5 gm
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