18 results
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty
#Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Assessment of Nonalcoholic ... Patients With Nonalcoholic ... Fatty #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... in fetal free fatty ... → Intermediate fatty ... iMedEducation #AFLP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP ... Burak @kwburak #LFTs
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute Fatty ... of Pregnancy (AFLP ... plasma exchange 3) Fatty ... TTPHUS #HELLP #AFLP
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... #FunctionTest #LFTs
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Prevalence of Nonalcoholic ... progressive type of nonalcoholic ... fatty liver disease
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
Pathogenesis of Nonalcoholic ... to develop in fatty
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Hemochromatosis - Nonalcoholic ... fatty liver disease
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
hemorrhage Acute Fatty ... of Pregnancy (AFLP ... Hepatic imaging: Fatty ... diagnosis #icp #HELLP #AFLP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... (Alk phos/ULN ALP ... • AST/ALT > ALP ... disease • If ALP ... transaminitis #LFTs