3053 results
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
for Three Common Causes ... of Shock HEMORRHAGIC ... SHOCK • Ensure ... inotropic support; norepinephrine ... vasopressor support with norepinephrine
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
increased MAP Norepinephrine ... first agent in shock ... • Higher doses cause ... line in septic shock ... cAMP/cGMP • Causes
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
SEPSIS AND SEPTIC SHOCK ... • 49 million cases ... COMMON CAUSES + ... all suspected cases ... Vasopressors: Norepinephrine
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
and Inotropes Norepinephrine ... : Distributive shock ... ), Cardiogenic shock ... , Shock where ↑ ... Bradyarrhythmias, Some cases
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... compensatory responses to shock ... Shock can be caused ... The cause of shock ... #Differential #Causes
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... and etiology of shock ... Ino-Constrictors: Norepinephrine ... Nesiritide 3) Treat shock ... #Vasopressors #shock
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Inotropes • Norepinephrine ... pressor added in shock ... in refractory shock ... in setting of shock ... - Cardiogenic shock
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock ... Hypovolemic Shock ... Cardiogenic Shock ... diagnosis #algorithm #causes
Budd Chiari Syndrome
Hepatic vein obstruction. Can be caused by thrombosis or sometimes a tumour. Can lead
Can be caused by ... Can lead to shock ... Syndrome #Diagnosis #Causes
Occult Causes of Non-Response to Vasopressors

vital disclaimer: the cognitive response to hypotension should not be reaching
Occult Causes of ... response -> cognitive pause ... toxicologic - 2nd cause ... shock #Diagnosis ... #Differential #Causes