39 results
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Lab patterns seen ... A table of lab ... values compiled ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... See the lab values ... MetabolicEmergency #Genetics #Pathophysiology ... #Diagnosis #Algorithm
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Differential Diagnosis Algorithm ... Hemoglobin: • Males ... Hypoxia-driven: Cardiac/pulmonary ... ), TEMPI (VEGF normal ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... values: WBC >100k ... Lysis Syndrome: • Pathophysiology ... values: Elevated ... diagnosis #management #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
and Management Algorithm ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... Diagnosis #Management #Algorithm ... #hematology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... History/Physical/Labs ... • Heart size: Normal ... ECHO: • Normal ... chamber size • Normal
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... With associated pulmonary ... differential #diagnosis #algorithm ... #rheumatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... artery biopsy • Lab ... values supporting ... hematologic malignancies
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm
Pulmonary Arterial Hypertension
 • Idiopathic
 • Associated with:
Causes of Pulmonary ... Differential Diagnosis Algorithm ... Pulmonary Arterial ... Disease - Portal ... Miscellaneous: • Hematologic