13 results
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Lab patterns seen ... A table of lab ... values compiled ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #InbornErrors
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... See the lab values ... #Diagnosis #Algorithm ... #Differential # ... Table #IEM #NICU #InbornErrors
Gynecomastia - Differential Diagnosis a
nd Workup Algorithm
Gynecomastia is common in clinical practice, affecting ~50% of males
Gynecomastia - Differential ... Diagnosis a nd Workup ... Algorithm Gynecomastia ... affecting ~50% of males ... Labs: TSH, Cr, LFTs
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... Returning Traveler’ algorithm ... artery biopsy • Lab ... values supporting
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... wasting PBC Labs ... bile ducts Differential ... cholangitis #diagnosis #workup
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... can have extra nodal ... pattern of spread, B symptoms ... Classification #pathophysiology ... #algorithm
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Kidneys, Liver • Labs ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... - Core temp normal
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... permanent alopecia Differential ... Cytopenias • Cardiac valve ... Induced Lupus: • Symptoms ... flares • CRP normal
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: • Labs ... Diagnosis: >3 symptoms ... initiation • Differential ... 500 mg QD until normal
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... that a one-off value ... exogenous, EPO levels: normal ... #workup #hematology