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diagnosis differential management rheumatology causes mds myelodysplastic workup activation acute aplastic apml cell chemistry chronic cll common cvid differentiation elevatedmcv
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Myelodysplastic Syndromes ... WBCs - Normal ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
: - Hepatitis ... (MDS) (normal or ... ) Labs: • Peripheral ... Treatment: ... #oncology #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... Infiltrative Labs ... - If both are normal ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... - If both are normal ... of ALP • Near normal ... • Gilbert's syndrome ... #differential #Hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... Diagnosis #causes #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: • Labs ... 500 mg QD until normal ... diagnosis #management #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Noninfectious hepatitis ... Cytopenias • Cardiac valve ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... , Serositis Labs
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