18 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: • Labs ... Renal Failure Treatment ... 500 mg QD until normal ... diagnosis #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... Cytopenias • Cardiac valve ... Erythematosus #Diagnosis #Rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... importantly, bedside ultrasound ... is vital while lab ... Cardiac cath if acute ... icu #clinical #pharmacology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... Thrombocytopenia - Normal ... + Bleeding Treatment ... - APTT < 1.5 x normal
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Hemolysis on labs ... Transfusion Related Acute ... Babesiosis & vCJD (varies ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Hemolysis on labs ... Transfusion Related Acute ... Babesiosis & vCJD (varies ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... megakaryocytes and a normal ... aplastic anemia) Labs ... aplastic anemia Treatment ... result from low blood
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
breath sounds • Rales ... anemia • Sputum/Blood ... CXR upright or lat ... - Switch to oral ... hemorrhage • Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
CLL Labs: 1. ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology