30 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Bridging #Dosing #Oral ... #Anticoagulant ... #Loading #DVT #Pharmacology ... #Hematology
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
Direct-acting oral ... anticoagulants ... DOACs) for VTE treatment ... Table #DOAC #Anticoagulants ... VTE #Management #Pharmacology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #AntiCoagulant
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral ... anticoagulants ... anticoagulant; ... Anticoagulation #Management #Hematology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
Choice of anticoagulant ... for treatment of ... • Once a day oral ... Pregnancy - LMWH #anticoagulant ... anticoagulation #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... anticoagulants ... commonly available lab ... interruption per treatment ... #pharmacology #
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
consider withholding anticoagulant ... decision to continue anticoagulant ... DOAC, direct oral ... anticoagulant; ... Anticoagulation #Management #Hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
treatment; volume ... Idarucizumab - Humanized Fab ... Reversal #NOAC #Oral ... #hematology #management ... #pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
or priapism • Lab ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Cerebritis: Labs ... Puncture, EEG Treatment ... Pathway - Aspirin, anticoagulants ... CNS #neurology #rheumatology ... diagnosis #management #treatment