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management diagnosis doac hematology syndrome abscess algorithm apml arteritis cardiology causes chf clinical criticalcare differentiation erythematosus foamed fungal gca giantcell
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... anticoagulants ... commonly available lab ... interruption per treatment ... #pharmacology #
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
treatment; volume ... Idarucizumab - Humanized Fab ... Reversal #NOAC #Oral ... #hematology #management ... #pharmacology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Cytopenias • Cardiac valve ... , Serositis Labs ... Erythematosus #Diagnosis #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Diagnosis: • Labs ... initiation • Differential ... Renal Failure Treatment ... 500 mg QD until normal
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
include Crackles/Rales ... importantly, bedside ultrasound ... is vital while lab ... #diagnosis #differential ... icu #clinical #pharmacology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... 50 in GCA, but normal ... values increase ... Treatment of GCA ... them, but urgent rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
breath sounds • Rales ... CXR upright or lat ... - Switch to oral ... Lung Abscess Differential ... Abscess #pulmonary #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... : • Severe oral ... Sjogrens #Syndrome #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Histoplasmosis Treatment ... Diagnosis: • Labs ... and Ohio River valleys ... level • A low or normal
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