9 results
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... anticoagulants ... commonly available lab ... #Treatment #pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
treatment; volume ... Idarucizumab - Humanized Fab ... Reversal #NOAC #Oral ... #hematology #management ... #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
importantly, bedside ultrasound ... is vital while lab ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: • Labs ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
breath sounds • Rales ... CXR upright or lat ... - Switch to oral ... Lung Abscess Differential ... Abscess #pulmonary #differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... 50 in GCA, but normal ... values increase ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
crusade against “Ab ... ”Normal Saline continues ... #foamed #criticalcare ... #management #diagnosis ... #treatment #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... Diagnosis: • Labs ... and Ohio River valleys ... level • A low or normal ... Fungal #Diagnosis #Management