15 results
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Fever (75%) • Encephalopathy ... enzymes ↑ • Mild anemia ... HIV-1 RNA viral ... antibody test) Treatment ... #HIV #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
(MDS) (normal or ... Treatment: ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... ) • Systemic symptoms ... lesion • CNS infection ... #Algorithm #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... anemia • Cold ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... CTD (SLE) - Viral ... infections - ... #hematology #rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Infections: - ... Viral: VZV, HSV, ... MCTD, Sjogren syndrome ... #algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... • Parvovirus infection ... blood cells appear normal ... #diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... : Infection (sepsis ... 500 mg QD until normal ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology