29 results
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Fever (75%) • Encephalopathy ... Most common: Oral ... HIV-1 RNA viral ... antibody test) Treatment ... #HIV #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
quinine, etc) - Viral ... : HIV, HCV, EBV, ... infiltration: malignancy, infection ... antiphospholipid syndrome ... #Framework #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Diagnosis Framework ... Antimicrobial treatment ... encephalopathy ... #HIV #CNS #Infections ... opportunistic #InfectiousDiseases
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... ) • Systemic symptoms ... lesion • CNS infection ... #Algorithm #neurology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... CTD (SLE) - Viral ... infections - ... • HCV, HBV Not ... #hematology #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... CAS): - Due to Viral ... - Polyclonal - Viral ... Mycoplasma, EBV, HIV ... hemolytic #anemia #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
(MDS) (normal or ... aplastic anemia Treatment ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... common infections ... #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Encephalopathy ... • Depressive symptoms ... Diagnosis: MRI ... The clinical syndrome ... dementia #AIDS #Neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... : Infection (sepsis ... 500 mg QD until normal ... #management #hematology