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diagnosis management differential dermatology rheumatology diffuse druginduced hairloss hematology pathophysiology acromegaly antiphospholipid apls comparison complications dil erythematosus focal hypercoagulable hyponatremia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Photosensitivity, Alopecia ... , oral ulcers, Lupus ... - CRP: Usually normal ... • Immunologic Workup ... life-threatening • Treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... Photosensitivity, Alopecia ... , oral ulcers, Lupus
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... hair follicles -> causes ... mechanism) -> Alopecia ... #SLE #Mucocutaneous
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... - Drugs • Oral ... • Discoid lupus ... #causes
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... Lupus Nephritis ... proteinuria (<3.5g/d, normal ... treat non-renal SLE
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... Panhypopituitarism Treatment ... Differential #Diagnosis #Algorithm ... #endocrinology ... #causes #pediatrics
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... - Drugs • Oral ... Differential #Diagnosis #Algorithm ... #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Causes #dermatology
Management of Hyponatremia Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125 Give
improving adequately Normal ... SIADH — look for cause ... give specific treatment ... Hyponatremia #Management #algorithm ... #treatment #sodium
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... some time, let’s see ... exogenous, EPO levels: normal ... about secondary causes ... #workup #hematology
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