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lupus signs sle symptoms erythematosus differential disease summary syndrome treatment antinxp2 aortoenteric arteritis autoantibodies behcet cardiology classification common comparison cvid
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... Endocarditis, Aortic ... erythematosus #signs ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... - CRP: Usually normal ... Workup: - ANA ... #rheumatology
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
and Management ... the duodenum Clinical ... Signs/Symptoms: ... no matter how long ... compression of AAA
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ... Myositis 4% - Lung ... autoantibodies #signs ... #differential #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... female, asian • Systemic ... biliary, renal, lung ... #management #phenotypes ... workup #treatment #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... CRP - Usually normal ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... sedimentation rate + Normal ... Differential Diagnosis ... flares • CRP normal ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Diagnosis = clinical ... 50 in GCA, but normal ... them, but urgent rheumatology ... #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... - Recurrent oral ... purpura: strong sign ... LFT • ESR • ANA ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... hemolytic anemia) • Systemic ... levels are within normal ... #diagnosis #management
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