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differential causes abnormal algorithm prolonged pt treatment dic disseminated hodgkins intravascular laboratory lymphoma syndrome anemia aplastic apml bleeding bruising classification
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Coagulation Tests ... #Algorithm #Coagulation ... #Abnormal #APTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PTT, Normal PT ... , Normal PT (INR ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... aggregation PT, aPTT ... consumption of coagulation ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... hemosiderin • PT/aPTT ... normal • DAT ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
INR < 2.3 - APTT ... < 1.5 x normal ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... intravascular coagulation ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... amyloidosis #Abnormal ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... marrow) -dys- (abnormal ... acute leukemia Management ... #Management #treatment ... #hematology #oncology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... may be normal in ... antigen (vWF:Ag) are normal ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Hematology
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