55 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... K Antagonists, Heparin ... ISNeducation #Abnormal ... #APTT #prolonged ... #diagnosis #hematology
Prolonged APTT - Diagnostic Algorithm

#Prolonged #APTT #PTT #abnormal #Diagnosis #Algorithm #hematology
Diagnostic Algorithm ... #Prolonged #APTT ... #PTT #abnormal ... #Diagnosis #Algorithm ... #hematology
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... PT - Prolonged aPTT ... PT - Prolonged aPTT ... #Coagulation #Abnormal ... #Hematology #Diagnosis
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Plasma → Recheck abnormal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT ... normal • DAT ... Management #Algorithm #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis ... #differential #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... aPTT (prolonged ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal ... Target Cells, Normal ... WBCs - Normal ... Deficiency - Abnormal ... Algorithm #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #Causes #diagnosis ... #differential #hematology