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diagnosis smear oncology rouleaux gammopathy mgus algorithm anemia aplastic biopsy blood bonemarrow causes cell classification coagulation common cryofibrinogenemia cvid dic
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
extensive rouleaux formation ... leukemia #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... ” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Hematology
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
lipid-dependent yeasts Clinical ... antifungals • Oral ... Tinea #Versicolor #Dermatology ... #SkinRash #Diagnosis ... #Management
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
protein <1.5 gm/dL, normal ... whom there are no clinical ... algorithm #diagnosis #management ... #hematology #multiplemyeloma
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
fatigue, bone pain, abnormal ... ) • Rouleaux formations ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Megaloblastic neutrophils in bone marrow. So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
times the size of normal ... BoneMarrow #Smear #Hematology ... #Pathology #Clinical
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... significant fibrin clot formation ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Biopsy: Typical pathologic ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and M panel Management ... levels are within normal ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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