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diagnosis differential management algorithm workup classification hemolysis leukemia microscopy pathology blood intravascular monoclonal rheumatology bloodsmear chronic dermatology extravascular hodgkins liver
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal ... peripheral smear ... Anemias (AIHAs) ... Diagnosis #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Diagnosis #Algorithm #Causes ... #Hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... cells: Sickle cell ... #Analysis #hematology ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... non-specific red cell ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... ) (e.g. lupus, CLL ... differential #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... • Sickle cell ... anemia • ... #Hematology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants). - Dr. Abubaker Elshaikh @ElshaikhMD #SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • ... WBCs - Normal ... Diagnosis #Algorithm #Causes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... RBC Production - Normal ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
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