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diagnosis differential management algorithm classification pathology blood microscopy workup bloodsmear chronic cll dermatology hemolysis hodgkins intravascular lymphocytic lymphoma mds myelodysplastic
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal ... peripheral smear ... Anemias (AIHAs) ... Diagnosis #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Diagnosis #Algorithm #Causes ... #Hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
anemia. ... DIC is a clinical ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... anemia • ... Diagnosis #Algorithm #Causes ... #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology ... #Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • ... WBCs - Normal ... Diagnosis #Algorithm #Causes ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... RBC Production - Normal ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... #hematology #secondary
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