62 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Reticulocytes, smear ... MAHA likely: • Smear ... hemosiderin • PT/aPTT normal ... #Algorithm #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... cells: Sickle cell disease ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Blood Smear • ... • Pancreatic Disease ... WBCs - Normal ... • Liver Disease ... Algorithm #Causes #Hematology
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Von Willebrand Disease ... - Clinical Presentation ... Diagnosis and Management ... VonWillebrand #Disease ... #hematology #treatment
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... RBC Production - Normal ... Anemia of Chronic Disease ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bleeding disorder Clinical ... PT/INR • Normal ... VonWillebrand #Disease ... #Diagnosis #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... also arise in normal ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
, Drugs, Liver Disease ... Electrolytes: Wilson's disease ... Peripheral Blood Smear ... ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... marrow) -dys- (abnormal ... acute leukemia Management ... #treatment #hematology ... #oncology