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management chronic cll differential formation hodgkins lymphocytic lymphoma mds myelodysplastic smear treatment workup anemia aplastic bandemia blood causes cbc cell
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... with extensive rouleaux ... #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... formation” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Formation #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... marrow) -dys- (abnormal ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... immunophenotype Clinical ... #oncology #hematology ... #hemeonc #diagnosis
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
fatigue, bone pain, abnormal ... bleeding) • Rouleaux ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
: < 1% Clinically ... Differential Diagnosis ... Tissue damage • Leukemia ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... syndrome (MDS) (normal ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... treatment #management #hematology
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