132 results
diagnosis differential causes algorithm management oncology workup dermatology ascites disorders gastroenterology hemolysis pathophysiology treatment vitaminb12 abnormal blood cirrhosis hemolytic iron
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... with Pancytopenia ... lauraebrown #Pancytopenia ... #Syndromes #BoneMarrow ... #diagnosis #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... deficiencies #Pancytopenia ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Differential #Diagnosis #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Microangiopathic Hemolytic Anemias ... • Early Iron Deficiency ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Dietary Deficiency ... Myelodysplastic Syndromes ... WBCs - Normal ... B12 and Folate Deficiency ... Algorithm #Causes #Hematology
Complications of Portal Hypertension • Hepatic Encephalopathy • Pulmonary: Hepatopulmonary syndrome, Portopulmonary hypertension, Hepatic hydrothorax •
Complications of Portal ... Hepatopulmonary syndrome ... Hypersplenism, Pancytopenia ... Renal: Hepatorenal syndrome ... Complications #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... some patients) Normal ... , Folate deficiency ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... , GATA2 deficiency ... , CTLA4 deficiency ... (MDS) (normal or ... #oncology #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... Acquired Aplastic Anemia ... marrow failure syndrome ... Diagnosis #Algorithm #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
80 fL) • Iron Deficiency ... Chronic Disease Normal ... 100 fL) • B12 Deficiency ... • Folate Deficiency ... Algorithm #Causes #Hematology
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