20 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... • Muscular: normal ... CK, normal biopsy ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... study (aPTT may be normal ... antigen (vWF:Ag) are normal ... Avoid meds that ... #treatment #hematology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... lesions (a), Brain: normal ... corticosteroids TREATMENT ... - Typical MS-like ... #treatment #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... can have extra nodal ... Responsive to Treatment ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Boxer's Fracture - ED Management
Be sure to assess for wounds in patients with fractures of the
Fracture - ED Management ... prophylactic antibiotic treatment ... tenderness over dorsal ... MH/CCF/CWRU EM ... #Orthopedics #MSK
Interphalangeal Joint Dislocation
Interphalangeal joint dislocations almost always occur dorsally, look for associated avulsion fractures! Here's a
dislocation, due to EDS ... tendon) • ED Management ... MH/CCF/CWRU EM ... XRay #Diagnosis #Management ... #Orthopedics #MSK
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
excrete water normally ... Then, ask 3 questions ... approach to the differential ... #Hyponatremia #Differential ... #management #nephrology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... immunologic assay - MuSK ... - Symptomatic Treatment ... immunosuppressants - Meds ... Gravis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Manifestations: • Oral ... Behcet disease) Differential ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology