31 results
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... production -> Corneal ... Xerophthalmia - abnormal ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
hyperkalemia) BRASH Treatment ... • Aggressive treatment ... balanced fluids" > normal ... BRASH #Syndrome #diagnosis ... #management #pathophysiology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... • Muscular: normal ... CK, normal biopsy ... • Ocular: uveitis ... #management #treatment
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... can have extra nodal ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... cardiomyopathy, Horner ... Guillain-Barre Diagnosis ... CSF PROTEIN - NORMAL ... #management #treatment
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Pathophysiology: ... • Normal exercise ... troponin elevation Diagnosis ... tests in cath lab Treatment ... #management
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... • Vestibulo-ocular ... movements; also normal ... caseyalbin #PhysicalExam
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... • Delusions Ocular ... vasculitis Treatment ... #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... 500 mg QD until normal ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #management #signs