12 results
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Manifestations of Monoclonal ... Systemic amyloidosis, Nodular ... Cold agglutinin disease ... manifestations #dermatology ... #skin #clinical
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Systemic Symptoms (DRESS ... ) Syndrome Treatment ... , IVIG etc • Skin ... topical steroid +/- oral ... #Management #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... characterized by extensive skin ... Skin involvement ... Oral/IV Glucocorticoids ... #Syndrome #dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... response to local skin ... test (this is a skin ... : monoclonal TNF-aIpha ... #diagnosis #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Cryoglobulinemic, Hypo/normo-complementemic ... Sneddon-Wilkinson disease
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
Angioedema • DRESS ... Preeclampsia Dermatologic ... • Sunburn • DRESS ... Trauma: • Ocular ... Differential #Diagnosis #PhysicalExam
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Neurologic disease ... nerve palsy • Horner ... lens wearing • Ocular ... effect of some abnormal ... Redundant eyelid skin
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
sites such as the collar ... palmoplantar pustulosis: oral ... disease. ... Rheumatology #diagnosis #management ... #Dermatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... pulmonary emboli, and ocular ... Antiphospholipid syndrome ... Warfarin-induced skin ... #rheumatology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... gland) biopsy • Ocular ... amyloidosis, PAH Skin ... Pharmacologic: • Severe oral ... Rheumatology #Diagnosis #Management