14 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Myopathy (Also caused ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... hair follicles -> causes ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... arthritis - SLE ... Aneurysmal bone cyst ... - Synovium - Oral ... differential #diagnosis #msk
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
Popliteal (Baker’s) Cyst ... intra-articular knee ... Popliteal #BakersCyst #MSK ... #pathophysiology ... #signs #symptoms
Baker's Cyst on POCUS 
63yo w p/w pain and swelling behind knee.  Probe on knee
Baker's Cyst on ... POCUS 63yo w p/ ... , and bam - POCUS ... Sign of intraarticular ... #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... Areflexia (loss of normal ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #signs
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Valgus position of knee ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis ... #msk
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Jaundice (later manifestation
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... - Core temp normal ... differential #diagnosis #causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... anterior/posterior MSK ... ), liver (pain/abnormal ... Diagnosis #Management #Signs ... #Symptoms