17 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative ... receptor] • Normal ... Platelet #Defects #comparison ... #differential #diagnosis ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Effusions: - Hematologic ... - Synovium - Oral ... #differential #diagnosis ... #msk #physicalexam
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... also arise in normal ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... of about 30% of normal ... examination; nonspecific symptoms ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... von Willebrand syndrome ... Inherited: • Factor ... #Differential #Diagnosis ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
thymoma DDX: • Inherited ... (MDS) (normal or ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Hepatic imaging: Normal ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... 500 mg QD until normal ... Differentiation #Syndrome ... #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... thromboembolism • Inherited ... • Drugs: - Oral ... • Nephrotic Syndrome ... pathophysiology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... can have extra nodal ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... pathophysiology #Hematology