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hematology syndrome rheumatology neurology oncology dermatology gastroenterology differential pulmonary chronic cirrhosis clinical summary symptoms activetb acute algorithm anemia aplastic barre
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
Algorithm for the Management ... drainage plus oral ... erysipelas with no focus ... antibiotic treatment ... SSTIs #Algorithm #Management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... : • Infectious ... CK, normal biopsy ... #diagnosis #management ... #treatment #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... risk-stratification • Risks: infection ... only curative treatment ... #Management #treatment ... #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... • Autoimmune diseases ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... : • Recurrent infections ... Symptomatic anemia Diagnosis ... #management #treatment ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... conditions Diagnosis ... and M panel Management ... levels are within normal ... #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • ALT & AST normal ... fungal, viral infections ... #workup #hepatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... present, symptoms, signs ... concentration in the normal ... von Willebrand disease ... #treatment #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... study (aPTT may be normal ... antigen (vWF:Ag) are normal ... #Management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment
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