16 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... CRP - Usually normal ... constitutional symptoms ... Lupusreference #druginduced ... #lupus #sle #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #CNS #neurology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... sedimentation rate + Normal ... permanent alopecia Differential ... : • Symptoms limited ... flares • CRP normal
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Behcet disease) Differential ... aphthae : SLE, ... #diagnosis #management ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Guillain-Barré syndrome ... GBS), systemic lupus ... erythematosus (SLE ... Stop statin • Oral ... myopathy #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... skin (16-32%): lupus ... ), liver (pain/abnormal ... Sarcoidosis #Diagnosis #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... Behcet disease - SLE ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... #diagnosis #management ... #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... - Recurrent oral ... such as systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE