22 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... - Drugs • Oral ... Secondary to Skin Disease ... • Discoid lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Photosensitivity, Alopecia ... , oral ulcers, Lupus ... - CRP: Usually normal ... life-threatening • Treatment ... Evolution: Chronic disease
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Capitis - Skin Disease ... : Discoid lupus ... : Lupus erythematosus ... , Loose anagen syndrome ... • Drugs: Oral
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... Photosensitivity, Alopecia ... , oral ulcers, Lupus ... Evolution: Chronic disease ... #sle #comparison
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... and permanent alopecia ... Malignancy (e.g. hematologic ... • Nonscarring alopecia ... vein thrombosis Hematologic
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Systemic #Lupus ... #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... cerebritis #diagnosis #management ... #treatment
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 • Lupus erythematosus
 • Lichen
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... • Loose anagen syndrome ... - Drugs • Oral ... #dermatology #Differential
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Lupus Nephritis ... proteinuria (<3.5g/d, normal ... for worsening disease ... #Treatment #management