41 results
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Seronegative Inflammatory ... Systemic Rheumatic Disease ... , Inflammatory Myopathy ... Arthropathy: Gout, CPPD ... Differential #Diagnosis #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... and can activate inflammatory ... Inflammatory Arthritis ... Gout #Comparison #rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Non-Malignant • Amyloidosis ... • Gaucher's Disease ... Glycogen Storage Disease ... myelofibrosis) Inflammatory ... Algorithm #Causes #Hematology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
(AA) → Chronic Inflammatory ... Clinical suspicion ... the extent of disease ... Clinical Manifestations ... • Circulating inflammatory
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... and can activate inflammatory ... Monoarticular inflammatory ... Inflammatory Arthritis ... #Rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... , PRES Pathophysiology ... Treatment: • Inflammatory ... CNS #neurology #rheumatology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pathogenesis and clinical ... pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... likely it will be clinically ... Drug-Induced, Inflammatory ... Bowel Disease, ... ANA #patterns #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... production of pro-inflammatory ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
background of a highly inflammatory ... release of pro-inflammatory ... fever syndromes Clinical ... Fever is the main clinical ... #Rheumatology