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rheumatology management differential neurology vasculitis algorithm classification cord disease disorders erythematosus lupus manifestations ms neuromyelitis nmo optica polychondritis relapsing sclerosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... pain/pain upon eye ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neuritis • Partial myelitis ... • Or brainstem syndromes ... Signs and symptoms ... patients with clinically ... stimulation Clinical
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
inflammation of multiple ... : Inflammatory eye ... syndrome (Clinical ... #Syndrome #diagnosis ... #management #signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... • Bilateral signs ... and/or symptoms ... suggestive of multiple ... Demyelination: - Multiple
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Weight loss (50%) Eye ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... - Transverse myelitis ... - Sarcoidosis, Behcet ... MCTD, Sjogren syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Mononeuritis multiplex ... VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... purpura: strong sign ... Eye -> retinopathy
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... vasculitis • Behcet
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
eyes • Salivary ... salivary ducts Clinical ... , mononeuritis multiplex ... neuropathy, transverse myelitis ... phenomenon (16%) MSK
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... vessels (aorta) • Eyes ... , MDS & Multiple ... Sarcoidosis • Behcet
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