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hematology differential leukemia cll hemeonc hiv infectiousdiseases lymphocytic neurology syndrome associated dementia differentiation disorder emergencies fungal hand immune inflammatory mds
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... HIV / AIDS - Differential ... • IRIS might ... patients with IRIS ... #diagnosis #AIDS
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... involvement • 30%: CNS ... smear: Blasts APML ... Leukemia #Hematology #Oncology ... #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
treatment of HIV/AIDS ... be present: • AIDS ... pleural effusions, CNS ... weeks for most OI ... #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... : >3 symptoms, or ... : Infection (sepsis ... #diagnosis #management ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... “big & sticky” cells ... : CNS changes, headache ... #HemeOnc #Diagnosis
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
and infects the CNS ... in the CNS ○ ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
85% • < 50% in chronic ... yeast • At risk: AIDS ... especially the CNS ... MC: CNS CSF: • ... #Management #Infections
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... lymphocytes, smudge cells ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... weeks without infection ... phenomenon CLL Diagnosis ... #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... • Parvovirus infection ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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