13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... smear: Blasts APML ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... weeks for most OI ... #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
: >3 symptoms, or ... : Infection (sepsis ... #APML #diagnosis ... #management #hematology ... #oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... • IRIS might ... patients with IRIS ... #AIDS #opportunistic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... weeks without infection ... • Richter’s Syndrome ... #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... lymphocytes, smudge cells ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... if SSTI or port infection ... abdominal pain; full infectious ... “big & sticky” cells ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... • Depressive symptoms ... Diagnosis: MRI ... The clinical syndrome ... disorder #dementia #AIDS