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diagnosis hemeonc anemia aplastic cardiology cardiotoxicity checkpoint chronic classification cll differential differentiation emergencies hemophagocytic hlh hodgkins inflammatory inhibitor leukemia lymphocytic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... #management #hematology ... #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... weeks for most OI ... #IRIS #Immune ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Significance (IDUS) • Immune ... factor (GCSF) treatments ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... ): - Hematologic ... “big & sticky” cells ... : - Seen with AML ... (~20 %) and APL
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity Problem - Immune checkpoint inhibitors (ICIs) are associated with
Management of Immune ... checkpoint inhibitors (ICIs ... Cardiotoxicity with ICIs ... Cardiotoxicity #cardiology #oncology ... #management #treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... ingestion • B symptoms ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... activation of the immune ... Common Signs and Symptoms ... #Hematology #HemeOnc
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... vessels (aorta) • Eyes ... affected tissue Treatment ... #diagnosis #management
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