9 results
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Syndrome (IRIS) ... - Disseminated OI ... response to OI ... regulatory responses UCSD ... #Syndrome #IRIS
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory ... with exaggerated inflammatory ... increase in CD4+ cells ... with severe symptoms ... weeks for most OI
Examination of the right eye revealed an iris lesion 3 mm in diameter (Panel A, arrow),
Examination of the right eye ... revealed an iris ... moderate number of inflammatory ... cells in the anterior ... chamber, dilated iris
Hypopyon: A white layer of inflammatory cells which settles along the bottom of the anterior chamber
white layer of inflammatory ... cells which settles ... in front of the iris ... to a number of inflammatory ... from outside the eye
Endophthalmitis: Infection within the eye. This most commonly occurs via introduction of microbes from the outside
(e.g.
Infection within the eye ... white layer of inflammatory ... cells in the ... in front of the iris ... Goldberg, M.D. - UCSD
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... Imaging (if atypical symptoms ... sarcoid or other CNS inflammatory ... tears oint + TAPE eye ... within 4m #Bells
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
middle layer of the eye ... which includes the iris ... Valvular disease - Inflammatory ... diagnosis #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... Multinucleated giant cells ... • Progressive symptoms ... syndrome: Ocular inflammatory
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Inflammation of the iris ... visual acuity, eye ... photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... diagnosis #signs #symptoms