738 results
Thrombotic Microangiopathy (TMA) - Diagnosis and Management Algorithm

#Thrombotic #Microangiopathy #TMA #Diagnosis #Management #Algorithm #hematology
Microangiopathy (TMA ... Microangiopathy #TMA ... Management #Algorithm #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA ... Complement-mediated TMA ... - Drug-induced TMA ... Microangiopathy #TMA ... #hematology #differential
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
TTP from other TMA ... (vs. secondary TMA ... management #treatment #rheumatology ... #hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
B12 Deficiency: MMA ... Folate Deficiency: MMA ... Homocysteine #B12 #MMA ... VitaminB12 #diagnosis #hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology #
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-mitochondrial (AMA ... Endomyseal antibody (EMA ... diagnosis #table #rheumatology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
microangiopathies (TMA ... Complement-mediated TMA ... (DITMA) - TMA ... differential #diagnosis #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA ... Algorithm Suspected TMA ... Microangiopathy #TMA ... Management #Algorithm #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
TMA is a triad of ... and secondary TMA ... Primary TMA is due ... TTP is only TMA ... Microangiopathy #TMAs #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Non-infectious (malignancy, rheumatologic ... causes #Platelets #hematology