23 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Syndrome (MAS) ... arthritis (sJIA) • Adult-onset ... #Syndrome #Diagnosis ... #Management #Hematology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... -> Trauma, disc ... #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... diseases: SLE+++, Adult-onset ... #management #treatment
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Transverse Myelitis, Trauma ... heavy metals), Critical ... #differential #diagnosis ... #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
presents in young adults ... Presentation - Young adults ... • Or brainstem syndromes ... stimulation Clinical ... #management #neurology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Chondrodysplasia Neurologic ... Poliomyelitis Activity/ Trauma ... symptoms #signs #diagnosis ... #msk
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... common type in adults ... include a: • Neurologic ... II ○ Susac’s syndrome ... ○ MS, CVA •
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... also observed in adults ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Common in: Adults ... (often termed MAS-HLH ... Clinical Presentation ... Pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #management #treatment