8 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... • recurrent fractures ... Low ALP in adult ... collection with EDTA Pathophysiology
Adrenal hematoma/hemorrhage on FAST exam

Adult male with RUQ/side pain after MVC. Transient prehospital hypotension.  Has
on FAST exam Adult ... Has femur fracture ... Diagnosis/differential ... FAST #Positive #trauma ... #clinical #ultrasound
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Maternal Support - Critical ... #management #pathophysiology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... • Diagnostic ... • Fluid bolus (Adult ... Plan definitive management ... #Management #Workup
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Recent history of trauma ... protein C and S Pathophysiology ... organ damage Clinical ... #Coagulation #diagnosis ... #hematology