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rheumatology treatment erythematosus systemic disease signs symptoms syndrome activation adultonset ana antibodies antinuclear arteritis behcet causes cerebritis cns gca giantcell
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... #Management #Summary ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... #CNS #neurology ... #rheumatology # ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... SJIA], systemic lupus ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
33% of healthy adults ... likely it will be clinically ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... fraction < 20% Differential ... #management #treatment ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... permanent alopecia Differential ... rheumatoid arthritis, adult-onset ... Malignancy (e.g. hematologic
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Autoimmune diseases: SLE ... +++, Adult-onset ... #management #treatment ... #summary #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... skin injury) • Neurologic ... Behcet disease) Differential ... Oral aphthae : SLE ... #management #signs
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
and Management ... Summary Causes ... Rhabdomyolysis: • Trauma ... Dermatomyositis Clinical ... #Diagnosis #Management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... with systemic, neurologic ... Diagnosis = clinical ... very remarkable w/differential ... #Management
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