33 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... Complications: MAS ... #management #treatment
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
More common in adults ... : Serology (preferred ... Culture & GS, PCR Treatment ... #management #treatment ... #infectiousdiseases
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary Clinical ... osteomyelitis, trauma ... Treatment: admission ... washout • Healthy Adults ... pediatrics but NOT adults
Acute limb ischemia (ALI)

Rapid decrease in lower limb blood flow due to acute occlusion of peripheral
Critical Limb ischemia ... entrapment, or trauma ... pathophysiology: ... The twin Saints Comas ... #endovascular #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
presents in young adults ... Presentation - Young adults ... stimulation Clinical ... #management #neurology ... #treatment #MS
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... Low ALP in adult ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Medullaris Syndrome -> Trauma ... Injury #Syndromes #diagnosis ... #pathophysiology ... #orthopedics #neurology