44 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... : • Acute or Chronic ... disorders • Celiac disease ... Post-op surgery • Trauma ... effect following treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... infarction, Severe trauma ... #Differential #Diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... : • Infectious ... Complications: MAS ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Unknown cause Treatment ... #management #treatment
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - APLS • Acute ... Infectious Purpura ... Solar purpura - Trauma ... #hematology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... rarely occurs in adults ... cæxist with other infections ... KD #vasculitis #rheumatology ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... susceptibility, infectious ... #AOSD #rheumatology ... #treatment
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
septated hyphae, acute ... this morphology Treatment ... Diseases Fellows ... #Management #treatment ... #fungal #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... also observed in adults ... presents as an acute ... : • Infection ... #hematology