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management differential rheumatology causes hematology chronic microbiology oncology chagas msk pain stills trypanosomiasis activetb adultonset american aosd classification cll fuo
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
- Differential Diagnosis ... • Infection: ... Lupus, Rheumatoid arthritis ... , Sarcoidosis, Adult ... #Differential #Diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... /arthritis, Skin ... : • Infectious ... #treatment #rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Juvenile idiopathic arthritis ... leishmaniasis • Adult ... • Rheumatoid arthritis ... #Differential #Diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
- Differential Diagnosis ... • Giant cell arteritis ... • Trauma Non-infectious ... • Lyme disease ... • Whipple's disease
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... susceptibility, infectious ... : High spiking fever ... low ferritin, arthritis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
after surgery/trauma ... • Underlying disease ... concomitant infection ... 12-24 Hours • Fever ... concomitant infection
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... osteomyelitis, trauma ... necrosis, Lyme disease ... diagnosis Treatment ... washout • Healthy Adults
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
after surgery/trauma ... culture used to diagnose ... concomitant infection ... Acute Pseudogout: Treatment ... acute neck pain, fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... (sJIA) • Adult-onset ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... early evening • Arthritis ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment
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