10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... Ebola, Dengue), Fungal ... Kaposi's sarcoma • Rheumatologic ... hemoptysis • Trauma ... #pulmonary #causes
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... Noninflammatory • Trauma ... tuberculosis) • Fungi ... arthritis • Adult ... #MSK #rheumatology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
presentations: • Pulmonary ... this morphology Treatment ... vori Infectious Diseases ... #Management #treatment ... #fungal #infectiousdiseases
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Trauma (implantation ... Refractory FUO, Sino-pulmonary ... : • Optimal treatment ... Fusarium #Infections #infectiousdiseases ... #diagnosis #management
Blastomycosis Summary

Pathogen: 
 • Dimorphic fungus - Blastomyces dermatitidis or Blastomyces gilchristii.
 • The fungus lives
• Dimorphic fungus ... • The fungus ... camping) The Disease ... : • Pulmonary ... #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Common in: Adults ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... #Management #Hematology