18 results
management hematology hemophagocytic lymphohistiocytosis oncology arthritis chronic classification differential hemeonc infections leukemia lymphocytic microbiology signs stills summary symptoms syndrome workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... also observed in adults ... Low or absent NK cell ... • Bicytopenia Treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Common in: Adults ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... #Management #Hematology
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
More common in adults ... : Serology (preferred ... : • Severe Disease ... #management #treatment ... #infectiousdiseases
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... common leukemia in adults ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #hemeonc #diagnosis
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission ... washout • Healthy Adults ... pediatrics but NOT adults
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
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