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differential treatment disease hematology hemophagocytic hlh lymphohistiocytosis activation adultonset airway algorithm anatomy aosd arteritis arthritis chestpain contusion criticalcare ctchest emergencies
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Chest Pain - Differential Diagnosis Algorithm Cardiovascular Causes: - Outflow Obstruction • Aortic
- Differential Diagnosis ... Injury • Trauma ... - Neurologic/ ... ChestPain #Noncardiac #Cardiology ... #Differential #Diagnosis
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... #onset #Stills ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
diseases: SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... Noninflammatory • Trauma ... weeks) Can Be Caused ... arthritis • Adult ... onset Still's
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Generalized: • Chills ... Cerebral > Splenic, pulmonary ... Septic Emboli Cause ... Treat underlying cause ... #management #cardiology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fever, cough, chills ... symptoms • Rheumatologic ... Cough, fever, chills ... : • Serology for ... #Management #Infections
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... with systemic, neurologic ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... #Management
Causes of Myoclonus - Differential Diagnosis LOCALIZATION: • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced • Sub-Cortical:
Causes of Myoclonus ... , post stroke, trauma ... • Sub-acute: OMS ... hepatic, septic, pulmonary ... #Causes #neurology
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