13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
Facial Swelling ... - Differential Diagnosis ... polymyositis • Adult-onset ... Still's disease ... Subcutaneous emphysema Renal
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... arthritis (sJIA) • Adult-onset ... Still disease ... #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... #onset #Stills ... #rheumatology # ... management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Rhabdomyolysis: • Trauma ... Malaise - Muscle swelling ... #Management #causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... #Rheumatology # ... Diagnosis #Management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... • Soft tissue swelling ... Noninflammatory • Trauma ... arthritis • Adult ... onset Still's
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... Differentiation #Syndrome ... #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Still disease, ... APLA/LAC: • Renal ... #Rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Fever, chills, lack ... cutaneous lesions with swelling ... #Inflammatory #Syndrome ... #Management